Pyridine, 3-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]- - Names and Identifiers
Pyridine, 3-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]- - Physico-chemical Properties
Molecular Formula | C10H8F3N3
|
Molar Mass | 227.19 |
Storage Condition | 2-8°C |
Pyridine, 3-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]- - Introduction
3-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]-Pyridine is an organic compound with the chemical formula C11H8F3N3, and its molecular structure contains a pyridine ring and an imidazole ring. The following is information about the properties, use, preparation and safety of the compound:
Nature:
-Appearance: Colorless or light yellow solid
-Melting point: about 135-140°C
-Boiling point: about 354°C
-Solubility: Soluble in organic solvents such as ethanol, dimethyl sulfoxide and dichloromethane
Use:
- 3-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]-Pyridine is commonly used as an organic synthesis intermediate in the pharmaceutical field and can be used to prepare a variety of drugs and bioactive molecules.
-It can also be used as a reagent in organic synthesis reactions.
Preparation Method:
The preparation of
- 3-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]-Pyridine generally involves a substitution reaction with pyridine or imidazole.
-Typically, pyridine or imidazole is reacted with the corresponding methylating agent (e. g., methyl iodide) and trifluoromethylating agent (e. g., trifluoromethyl iodide) in dichloromethane or other suitable solvent under suitable reaction conditions to give the desired product.
Safety Information:
- 3-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]-Pyridine is an organic compound and should comply with general laboratory safety procedures.
-During use and storage, care should be taken to avoid contact with strong oxidants and strong acids to prevent dangerous reactions.
-in the operation should pay attention to avoid inhalation, ingestion or contact with skin and eyes, such as contact should be immediately washed with running water.
-If inhaled or ingested by mistake, you should seek medical treatment in time.
Please note that this information is for reference only. The specific operation should follow the operating procedures and safety guidelines of the professional laboratory.
Last Update:2024-04-09 15:17:59